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PreventionObjectives
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- Disseminate information on the benefits of screening for early detection to the public and health care providers. Current evidence-based screening tests include:
- Mammography for
- Endoscopy and/or fecal occult blood testing for
- Pap tests for
- Skin self-examination and physical examination for
- Other screening tests as developed
- Emphasize screening education in communities with identified .
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- Disseminate information on increased risk of:
- Diets low in fruits and vegetables, as diet is related to 30% of all cancers
- Breast, esophageal, and head and neck cancer with more-than-moderate alcohol use
- Colon and breast cancer with high dietary fat
- Lung cancer with radon exposure
- Lung, breast, cervical, kidney, head and neck, pancreas, colorectal and bladder cancer with tobacco use, from both primary and second-hand smoke exposure as tobacco exposure is related to 30% of all cancers
- Skin cancer with ultraviolet exposure
- Support programs increasing the general population’s knowledge regarding familial risk, genetic testing and counseling, treatment options, and best practices.
- Provide education to health care providers to increase use of appropriate family history risk assessment tools for individuals in the following high risk groups:
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Breast cancer
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Breast cancer, especially under age 50
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Male breast cancer
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Ovarian cancer at any age
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Jewish ancestry
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Non-medullary thyroid cancer
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Hereditary Breast/Ovarian Cancer (HBOC); Cowden Syndrome; Li-Fraumeni Syndrome; or Neurofibromatosis type 1
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Inherited mutations in BRCA1/2, PTEN, p53, or NF1 genes
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Colorectal cancer
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Colorectal and/or endometrial cancers, especially under age 60
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Ovarian cancer at any age
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Multiple colon polyps (10 or more on a single screening)
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Hereditary Non-Polyposis Colon Cancer (HNPCC, aka Lynch syndrome); Familial Adenomatous Polyposis (FAP); or MYH-Associated Polyposis (MAP)
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Inherited mutations in MLH1, MSH2, MSH6, PMS2, APC, or MYH genes
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Ovarian cancer
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Breast cancer, especially under age 50
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Ovarian cancer at any age
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Male breast cancer
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Jewish ancestry
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Hereditary Breast/Ovarian Cancer (HBOC); Hereditary Non-Polyposis Colon Cancer (HNPCC, aka Lynch syndrome)
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Inherited mutations in BRCA1/2, MLH1, MSH2, MSH6, or PMS 2 genes
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Melanoma
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Melanoma
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Thyroid cancer
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Thyroid or breast cancer
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Multiple Endocrine Neoplasia type II; Cowden syndrome
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Inherited mutations in RET or PTEN genes
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Prostate cancer
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Prostate cancer
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Endometrial cancer
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Colorectal and/or endometrial cancers, especially under age 60
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Ovarian cancer at any age
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Hereditary Non-Polyposis Colon Cancer (HNPCC, aka Lynch syndrome)
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Inherited mutations in MLH1, MSH2, MSH6, or PMS2 genes
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Strategies:
- Provide education to health care providers to increase use of appropriate assessment tools in the following high- risk groups:
- Breast cancer in women with first- degree relatives with breast cancer, especially under age 50 and/or ovarian cancer at any age
- Breast and ovarian cancer in women with BRCA1 and BRCA2 gene mutations
- Colorectal cancer in persons with first- degree relatives with colorectal cancer, especially at age less than 60
- Melanoma in persons with first-degree relatives with melanoma
- Prostate cancer in men with first- degree relatives with prostate cancer
- Thyroid cancer in persons with first- degree relatives with thyroid cancer or multiple endocrine neoplasia type II
- Support programs increasing the general population’s knowledge regarding familial risk, genetic testing and counseling, treatment options, and best practices.
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- Disseminate information on clinical trials via the Colorado Cancer Coalition website at about ongoing clinical trials in chemoprevention at the following sites; UCCC, CCRP, and RMCC.
- Support establishment of professional training mechanisms, which will increase knowledge about clinical trials.
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